You can use a Hand Tracker to make an object move with or respond to someone's hand, without scripting.
The Hand Tracker tracks a single hand - you can't have more than one Hand Tracker in a scene.
The hand needs to be quite close to the camera for the Hand Tracker to respond. For example, it won't track to hands of people far away.
Follow these steps:
You can use scripting to achieve other effects - for example, assigning an object's coordinates to the hand.
For scripting the object should be dragged into Camera, and out of Focal Distance.